Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546035 | 0.86 | F2RL3 (0.47) | F2RL3RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2546038 | 0.86 | F2RL3 (0.47) | F2RL3RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2549910 | 0.78 | ACACB (0.45) | F2RL3SMN1; SMN2ACACAACACBLMNA | |
| SCHEMBL2549907 | 0.78 | ACACB (0.45) | F2RL3SMN1; SMN2ACACAACACBLMNA | |
| SCHEMBL2548902 | 0.78 | F2RL3 (0.45) | F2RL3RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2548901 | 0.78 | F2RL3 (0.45) | F2RL3RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2551532 | 0.78 | ACACB (0.43) | F2RL3RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2551529 | 0.78 | ACACB (0.43) | F2RL3RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14734835 | 0.77 | SLC6A2 (0.41) | F2RL3SLC6A2SLC6A4HTR3AKCNH2 | |
| SCHEMBL2549644 | 0.75 | F2RL3 (0.41) | F2RL3RAB9ASMN1; SMN2TP53ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563765-A1 | BICYCLIC COMPOUND DERIVATIVES AND THEIR USE AS ACC INHIBITORS. | Takeda Pharmaceutical Company Limited (JP) | 2013-03-06 | — | — | EP | disclosed |