Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 18/20 | 0.56 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14886997 | 0.92 | PIM1 (0.50) | PIM1PIM2PIM3KDM4EMEN1 | |
| SCHEMBL14735288 | 0.91 | PIM1 (0.61) | PIM1PIM2PIM3KDM4EMEN1 | |
| SCHEMBL14735290 | 0.91 | PIM1 (0.61) | PIM1PIM2PIM3KDM4EMEN1 | |
| SCHEMBL14734942 | 0.86 | PIM1 (0.75) | PIM1PIM2PIM3 | |
| SCHEMBL14734945 | 0.86 | PIM1 (0.75) | PIM1PIM2PIM3 | |
| SCHEMBL14735018 | 0.84 | PIM1 (0.53) | PIM1PIM2PIM3KDM4EMEN1 | |
| SCHEMBL14735563 | 0.84 | PIM1 (0.54) | PIM1PIM2PIM3KDM4EMEN1 | |
| SCHEMBL14735565 | 0.84 | PIM1 (0.54) | PIM1PIM2PIM3KDM4EMEN1 | |
| SCHEMBL14887118 | 0.84 | PIM1 (0.49) | PIM1KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL14887057 | 0.84 | PIM1 (0.44) | PIM1PIM2PIM3MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565192-A1 | ANTICANCER AGENT | The University of Tokyo (JP) | 2013-03-06 | — | — | EP | disclosed |