Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.54 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486777 | 0.89 | TLR8 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL1486530 | 0.87 | TLR7 (0.73) | TLR7TLR8NUDT1 | |
| SCHEMBL1486567 | 0.87 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL1486516 | 0.85 | TLR8 (0.58) | TLR7TLR8NUDT1 | |
| SCHEMBL1486459 | 0.82 | TLR8 (0.59) | TLR7TLR8NUDT1 | |
| SCHEMBL1486446 | 0.81 | TLR7 (0.75) | TLR7TLR8NUDT1 | |
| SCHEMBL12315583 | 0.81 | TLR7 (0.56) | TLR7TLR8NUDT1 | |
| SCHEMBL1486528 | 0.81 | TLR7 (0.69) | TLR7TLR8NUDT1 | |
| SCHEMBL1486627 | 0.81 | TLR7 (0.55) | TLR7TLR8NUDT1 | |
| SCHEMBL1486702 | 0.80 | TLR8 (0.50) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658076-B1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2013-03-06 | — | — | EP | disclosed |