Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 19/20 | 0.51 |
| ▸ | DRD3 | P35462 | 11/20 | 0.51 |
| ▸ | DRD2 | P14416 | 19/20 | 0.50 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13013927 | 1.00 | HTR2A (0.51) | HTR2ADRD3DRD2HTR1AHTR7 | |
| SCHEMBL14748221 | 1.00 | HTR2A (0.51) | HTR2ADRD3DRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1971354 | 0.99 | HTR2A (0.50) | HTR2ADRD3DRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1971355 | 0.99 | HTR2A (0.50) | HTR2ADRD3DRD2HTR1AHTR7 | |
| SCHEMBL13013938 | 0.92 | HTR2A (0.50) | HTR2ADRD3DRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1970628 | 0.91 | HTR2A (0.49) | HTR2ADRD3DRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1970630 | 0.91 | HTR2A (0.49) | HTR2ADRD3DRD2HTR1AHTR7 | |
| SCHEMBL14748264 | 0.89 | HTR2A (0.50) | HTR2ADRD3DRD2HTR1AHTR7 | |
| SCHEMBL13013944 | 0.87 | HTR2A (0.56) | HTR2ADRD3DRD2HTR1AHTR7 | |
| SCHEMBL13013912 | 0.87 | HTR2A (0.52) | HTR2ADRD3DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334657-B1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2013-03-06 | — | — | EP | disclosed |