⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458341 | 1.00 | — | — | |
| SCHEMBL26046233 | 0.92 | TSHR (0.32) | — | |
| SCHEMBL4950916 | 0.83 | — | — | |
| SCHEMBL26371 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL27709593 | 0.79 | — | — | |
| Bromide SCHEMBL6666626 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL17152673 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7772637 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7772640 | 0.76 | — | — | |
| Bromide SCHEMBL6666625 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-113423710-A | Novel heterocyclic tricyclic derivative compound and use thereof | 韩美药品株式会社 | 2021-09-21 | — | — | CN | disclosed |
| US-20130059850-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130059850-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130059850-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-03-07 | — | — | US | disclosed |
| CN-102917707-A | Azaindole derivatives useful as modulators of FAAH | MERCK SHARP & DOHME | 2013-02-06 | — | — | CN | disclosed |