⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474578 | 0.84 | GRM4 (0.42) | — | |
| SCHEMBL3128568 | 0.77 | — | — | |
| SCHEMBL21645064 | 0.77 | — | — | |
| SCHEMBL4585500 | 0.76 | CCR1 (0.46) | — | |
| SCHEMBL6750865 | 0.74 | CCR1 (0.44) | — | |
| SCHEMBL29956097 | 0.74 | CCR1 (0.44) | — | |
| SCHEMBL27903107 | 0.74 | GRM4 (0.52) | — | |
| SCHEMBL1717209 | 0.73 | — | — | |
| SCHEMBL6791381 | 0.73 | — | — | |
| SCHEMBL2051841 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020188122-A1 | Novel compounds | SMITHKLINE BEECHAM CORPORATION | 2002-12-12 | — | — | US | claimed |
| EP-1229035-A1 | Imine intermediates for the preparation of trisubstituted imidazole compounds with multiple therapeutic properties | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-07 | — | — | EP | claimed |
| CN-119432634-A | Saccharomyces cerevisiae engineering bacteria for synthesizing beta-carotene and construction method and application thereof | 北京化工大学 | 2025-02-14 | — | — | CN | disclosed |
| US-20230331770-A1 | ARGININE MODIFICATION AND CONJUGATION METHODS | Encodia, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
| US-11542256-B2 | Vinylheterocycles as Rho-associated coiled-coil kinase (ROCK) inhibitors | ANGION BIOMEDICA CORP. (US) | 2023-01-03 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20200231576-A1 | VINYLHETEROCYCLES AS RHO-ASSOCIATED COILED-COIL KINASE (ROCK) INHIBITORS | ANGION BIOMEDICA CORP. | 2020-07-23 | — | — | US | disclosed |
| CN-107311981-A | Show ketone of 2 aminopyrimidine 6 of active anticancer and antiproliferative activity and the like | 德西费拉制药有限责任公司 | 2017-11-03 | — | — | CN | disclosed |
| CN-105120864-B | 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-105120864-A | 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activity | DECIPHERA PHARMACEUTICALS LLC | 2015-12-02 | — | — | CN | disclosed |
| CN-102574864-B | Fused aminodihydropyrimidinone derivatives | EISAI R&D MAN CO LTD | 2015-04-29 | — | — | CN | disclosed |
| US-5593992-A | CYTOKINE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996040143-A1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0708768-A4 | TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES | SMITHKLINE BEECHAM CORP (US) | 1996-08-21 | — | — | EP | disclosed |
| CN-1129447-A | Trisubstituted imidazoles having multiple therapeutic effects | SMITHKLINE BEECHAM CORP (US) | 1996-08-21 | — | — | CN | disclosed |
| WO-1996021452-A1 | CERTAIN 1,4,5-TRI-SUBSTITUTED IMIDAZOLE COMPOUNDS USEFUL AS CYTOKINE | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-18 | — | — | WO | disclosed |
| WO-1996021654-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-18 | — | — | WO | disclosed |
| EP-0708768-A1 | TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002591-A1 | TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
| US-3969520-A | 2-Amino-4[2-(1-lower alkyl-5-nitro-2-imidiazolyl)vinyl]pyrimidines for treating protozoal and bacterial infections | ISTITUTO CHEMIOTERAPICO ITALIANO S.P.A. (IT) | 1976-07-13 | — | — | US | disclosed |