Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | PTGFR | P43088 | 11/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743579 | 0.97 | PTGFR (0.36) | KDM4EALDH1A1GAASLC22A12PTGFR | |
| SCHEMBL14743085 | 0.81 | IDO1 (0.39) | KDM4ESLC22A12PTGFRIDO1TACR3 | |
| SCHEMBL14743079 | 0.79 | IDO1 (0.40) | KDM4ESLC22A12PTGFRIDO1TACR3 | |
| SCHEMBL14743293 | 0.77 | IDO1 (0.40) | KDM4ESLC22A12PTGFRIDO1GLA | |
| SCHEMBL14742923 | 0.74 | IDO1 (0.43) | KDM4EPTGFRIDO1MEN1NPC1 | |
| SCHEMBL14743496 | 0.70 | TYMS (0.39) | — | |
| SCHEMBL14742741 | 0.69 | TACR3 (0.34) | PTGFRTACR3 | |
| SCHEMBL14743237 | 0.68 | NPY5R (0.36) | — | |
| SCHEMBL15156152 | 0.68 | PTGFR (0.38) | PTGFRIDO1RXFP1MEN1NPC1 | |
| SCHEMBL17973095 | 0.67 | TYMS (0.54) | KDM4EALDH1A1GAANPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030750-A1 | ANTIVIRAL COMPOUNDS | LUPIN LIMITED (IN) | 2013-03-07 | — | — | WO | disclosed |