SCHEMBL14744178

SCHEMBL14744178

COC(=O)[C@H](C)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36713 1.00
SCHEMBL2322217 1.00
SCHEMBL4476955 0.78 SMN1; SMN2 (0.41)
SCHEMBL690839 0.78 SMN1; SMN2 (0.48)
SCHEMBL5434607 0.78 SMN1; SMN2 (0.32)
SCHEMBL2007852 0.78
SCHEMBL952339 0.78 SMN1; SMN2 (0.32)
SCHEMBL482543 0.78
SCHEMBL1415223 0.78 SMN1; SMN2 (0.48)
SCHEMBL17068140 0.78 SMN1; SMN2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116621697-A Preparation method of dextrorotation 2- (2, 4-dichlorophenoxy) propionic acid 南京工业大学 2023-08-22 CN claimed
CN-112694403-B Method for preparing (R) - (+) -2- (4-hydroxyphenoxy) methyl propionate 锦州三丰科技有限公司 2023-04-18 CN claimed
CN-112812002-B Preparation method of (R) - (+) -2- (4-hydroxyphenoxy) propionic acid 锦州三丰科技有限公司 2022-12-09 CN claimed
EP-4648762-A2 PPARG MODULATORS University of Florida Research Foundation, Incorporated (US) 2025-11-19 EP disclosed
US-20250325550-A1 HETEROCYCLYLAMINES AS PI3K INHIBITORS INCYTE CORP (US) 2025-10-23 US disclosed
US-20250289823-A1 USE OF PYRAZOLOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PI3K-DELTA RELATED DISORDERS INCYTE CORPORATION 2025-09-18 US disclosed
EP-3888657-B1 HETEROCYCLYLAMINES AS PI3K INHIBITORS INCYTE HOLDINGS CORP (US) 2025-03-19 EP disclosed
US-20250026778-A1 GALACTOSIDE DERIVATIVE AS GALECTIN-3 INHIBITOR TIUMBIO CO., LTD. (KR) 2025-01-23 US disclosed
US-12201636-B2 Heterocyclylamines as PI3K inhibitors INCYTE CORPORATION (US) 2025-01-21 US disclosed
US-12152033-B2 Use of pyrazolopyrimidine derivatives for the treatment of PI3K-δ related disorders INCYTE CORPORATION (US) 2024-11-26 US disclosed
WO-2024151519-A2 PPARG MODULATORS UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) 2024-07-18 WO disclosed
US-9643984-B2 Method for the preparation of [1,2,4]-triazolo[4,3-a]pyridines AMGEN INC. (US) 2017-05-09 US disclosed
US-20160347769-A1 METHOD FOR THE PREPARATION OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES AMGEN INC. 2016-12-01 US disclosed
US-20160347769-A1 METHOD FOR THE PREPARATION OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES AMGEN INC. 2016-12-01 US disclosed
EP-2751059-B1 PROCESS FOR PREPARING DI-SUBSTITUTED SUCCINATES SAUDI BASIC IND CORP (SA) 2015-09-16 EP disclosed
WO-2014210042-A2 METHOD FOR THE PREPARATION OF (1,2,4)-TRIAZOLO(4,3-A)PYRIDINES AMGEN INC. (US) 2014-12-31 WO disclosed
US-8889898-B2 Process for preparing di-substituted succinates SAUDI BASIC INDUSTRIES CORPORATION (SA) 2014-11-18 US disclosed
US-20140194647-A1 PROCESS FOR PREPARING DI-SUBSTITUTED SUCCINATES SAUDI BASIC INDUSTRIES CORPORATION (SA) 2014-07-10 US disclosed
EP-2751059-A1 PROCESS FOR PREPARING DI-SUBSTITUTED SUCCINATES Saudi Basic Industries Corporation (SA) 2014-07-09 EP disclosed
WO-2013029767-A1 PROCESS FOR PREPARING DI-SUBSTITUTED SUCCINATES SAUDI BASIC INDUSTRIES CORPORATION (SA) 2013-03-07 WO disclosed