Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14745316 | 0.89 | FFAR1 (0.44) | FFAR1PPARGFFAR4 | |
| SCHEMBL14744838 | 0.89 | DAO (0.43) | FFAR1DAOMEN1KMT2AALDH1A1 | |
| SCHEMBL14745557 | 0.87 | KDM4E (0.44) | FFAR1PPARGDAOMEN1KMT2A | |
| SCHEMBL14745407 | 0.86 | DAO (0.51) | FFAR1DAOMEN1KMT2AALDH1A1 | |
| SCHEMBL14745595 | 0.86 | FFAR1 (0.42) | FFAR1PPARGDAOMEN1KMT2A | |
| SCHEMBL14745090 | 0.77 | FFAR1 (0.44) | FFAR1PPARGDAOKDM4EFFAR4 | |
| SCHEMBL14741336 | 0.77 | DAO (0.51) | FFAR1DAOMEN1KMT2ALMNA | |
| SCHEMBL14744817 | 0.75 | HSD17B10 (0.33) | FFAR1PPARGDAOALDH1A1KDM4E | |
| SCHEMBL14745184 | 0.74 | KDM4E (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL14745185 | 0.70 | PPARG (0.46) | FFAR1PPARGMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750504-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | claimed |
| WO-2013033258-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | claimed |