Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18867933 | 0.81 | AKR1C3 (0.65) | KDM4EAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL4972149 | 0.81 | AKR1C3 (0.65) | KDM4EAKR1C3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28164225 | 0.79 | AKR1C3 (0.62) | KDM4EAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL12592305 | 0.79 | KDM4E (0.55) | KDM4EAKR1C3ACHEALDH1A1MEN1 | |
| SCHEMBL14010446 | 0.78 | CYP17A1 (0.51) | KDM4ECYP17A1ALDH1A1MEN1KMT2A | |
| SCHEMBL13126150 | 0.77 | CYP17A1 (0.42) | ACHECYP17A1ALDH1A1MEN1KMT2A | |
| SCHEMBL19928242 | 0.77 | MEN1 (0.55) | KDM4ECYP17A1ALDH1A1MEN1KMT2A | |
| SCHEMBL22585545 | 0.76 | CYP17A1 (0.49) | KDM4ECYP17A1ALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL6001231 | 0.75 | CYP17A1 (0.41) | ACHECYP17A1ALDH1A1MEN1KMT2A | |
| SCHEMBL2901123 | 0.75 | AKR1C3 (0.51) | KDM4EAKR1C3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013032608-A1 | INDENO-FUSED RING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2013-03-07 | — | — | WO | disclosed |