Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746608 | 0.93 | PDE5A (0.77) | PDE5A | |
| SCHEMBL14746584 | 0.91 | PDE5A (0.79) | PDE5A | |
| SCHEMBL14754812 | 0.91 | PDE5A (0.78) | PDE5A | |
| SCHEMBL14746487 | 0.90 | PDE5A (0.80) | PDE5A | |
| SCHEMBL14754832 | 0.89 | PDE5A (0.73) | PDE5A | |
| SCHEMBL14746445 | 0.89 | PDE5A (0.75) | PDE5A | |
| SCHEMBL17541304 | 0.89 | PDE5A (0.75) | PDE5A | |
| SCHEMBL17541337 | 0.88 | PDE5A (0.74) | PDE5A | |
| SCHEMBL14746267 | 0.88 | PDE5A (0.76) | PDE5A | |
| SCHEMBL14746544 | 0.87 | PDE5A (0.82) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751106-B1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | BAYER IP GMBH (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-2751106-A1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013030288-A1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-07 | — | — | WO | disclosed |