Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756260 | 1.00 | MEN1 (0.43) | MEN1KMT2AL3MBTL1SLC5A2TSHR | |
| SCHEMBL14747265 | 1.00 | MEN1 (0.43) | MEN1KMT2AL3MBTL1SLC5A2TSHR | |
| SCHEMBL6654208 | 1.00 | MEN1 (0.43) | MEN1KMT2AL3MBTL1SLC5A2TSHR | |
| SCHEMBL18922697 | 0.87 | MEN1 (0.41) | MEN1KMT2AL3MBTL1TSHRCYP2C19 | |
| SCHEMBL15918074 | 0.86 | MEN1 (0.44) | MEN1KMT2AL3MBTL1SLC5A2CYP2C19 | |
| SCHEMBL20019604 | 0.83 | MEN1 (0.43) | MEN1KMT2AL3MBTL1TSHRCYP2C19 | |
| SCHEMBL12137914 | 0.82 | MEN1 (0.42) | MEN1KMT2AL3MBTL1SLC5A2TSHR | |
| SCHEMBL31728387 | 0.82 | MEN1 (0.42) | MEN1KMT2AL3MBTL1SLC5A2TSHR | |
| SCHEMBL10580919 | 0.79 | MEN1 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7145818 | 0.79 | MEN1 (0.38) | MEN1KMT2AL3MBTL1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |