Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357360 | 1.00 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL32662980 | 1.00 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL18286530 | 0.96 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL15879320 | 0.96 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL9439481 | 0.96 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL24587232 | 0.96 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL24587234 | 0.91 | MAPT (0.38) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL15366358 | 0.90 | TSHR (0.48) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL15366731 | 0.89 | MAPT (0.46) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL29752730 | 0.89 | MAPT (0.39) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |