Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 6/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105638 | 0.94 | MAPT (0.39) | LMNAMAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14747443 | 0.89 | PTPN1 (0.43) | LMNAMAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14747444 | 0.87 | PTPN1 (0.41) | MAPTPTPN1HRH2CXCR4FOLH1 | |
| SCHEMBL14747448 | 0.85 | FOLH1 (0.37) | PTPN1HRH2CXCR4NPC1USP2 | |
| SCHEMBL1105635 | 0.84 | MAPT (0.36) | LMNAMAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1105643 | 0.84 | PTPN1 (0.44) | LMNAMAPTMEN1KMT2APTPN1 | |
| SCHEMBL1105706 | 0.81 | PTPN1 (0.42) | MAPTPTPN1HRH2CXCR4FOLH1 | |
| SCHEMBL10118448 | 0.80 | CXCR4 (0.39) | PTPN1HRH2CXCR4FOLH1 | |
| SCHEMBL15827270 | 0.79 | MEN1 (0.41) | LMNAMAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14747449 | 0.77 | PTPN1 (0.44) | PTPN1HRH2NPC1USP2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |