Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462777 | 0.87 | RXFP1 (0.78) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL12260308 | 0.86 | KMT2A (0.68) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL10113885 | 0.86 | KMT2A (0.71) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL18166591 | 0.86 | MAPK1 (0.74) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL18166761 | 0.85 | MAPK1 (0.74) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL17744968 | 0.85 | RXFP1 (0.75) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL18166600 | 0.83 | MAPK1 (0.71) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL15375895 | 0.83 | KMT2A (0.74) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL10114347 | 0.83 | KMT2A (0.82) | KMT2AMEN1MAPK1RXFP1TP53 | |
| SCHEMBL12260301 | 0.82 | RXFP1 (0.71) | KMT2AMEN1MAPK1RXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389529-B2 | Methods and compositions for treating asthma | HYDRA BIOSCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |