SCHEMBL14747820

SCHEMBL14747820

CNC(=O)Nc1ccc(-c2sc3c(c2CN(C)Cc2ccccn2)c(=O)n(CCC(=O)OC)c(=O)n3Cc2c(F)cccc2F)cc1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780678 0.95 GNRHR (0.79) GNRHR
SCHEMBL14747822 0.93 GNRHR (0.67) GNRHR
SCHEMBL780410 0.89 GNRHR (0.78) GNRHR
SCHEMBL779864 0.88 GNRHR (0.81) GNRHR
SCHEMBL4053823 0.85 GNRHR (0.68) GNRHR
SCHEMBL4052410 0.84 GNRHR (0.67) GNRHR
SCHEMBL777759 0.83 GNRHR (0.87) GNRHR
SCHEMBL779746 0.83 GNRHR (1.00) GNRHR
SCHEMBL778069 0.82 GNRHR (0.92) GNRHR
SCHEMBL799481 0.81 GNRHR (0.83) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1591446-B1 Thienopyrimidine compounds and use thereof TAKEDA PHARMACEUTICAL (JP) 2013-03-06 EP disclosed