Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716232 | 0.88 | PDE4B (0.54) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| SCHEMBL14728301 | 0.88 | PDE4B (0.50) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL14716009 | 0.87 | PDE4B (0.53) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL14716171 | 0.87 | PDE4B (0.49) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| SCHEMBL14728293 | 0.83 | PDE4B (0.46) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| SCHEMBL14728297 | 0.77 | PDE4B (0.61) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| SCHEMBL14728302 | 0.76 | PDE4B (0.59) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| SCHEMBL14716461 | 0.76 | PDE4B (0.64) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| SCHEMBL14728315 | 0.75 | PDE4B (0.69) | PDE4BKDM4ECASP1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL14716134 | 0.75 | PDE4B (0.59) | PDE4BKDM4ECASP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565194-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2013-03-06 | — | — | EP | disclosed |