Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748430 | 0.93 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2528076 | 0.86 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL2532071 | 0.79 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL2528121 | 0.75 | CYP1A2 (0.38) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL2230030 | 0.73 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15012608 | 0.72 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2230578 | 0.70 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2527442 | 0.70 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2525481 | 0.70 | FGFR4 (0.36) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2528977 | 0.69 | PDE4B (0.37) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |