Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728385 | 0.78 | MAPK1 (0.76) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14748471 | 0.78 | MAPK1 (0.38) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14728371 | 0.72 | MAPK1 (0.74) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14748484 | 0.70 | MAPK1 (0.37) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14728219 | 0.68 | MAPK1 (0.77) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14748400 | 0.67 | MAPT (0.33) | KDM4EKMT2ANPSR1MAPTALDH1A1 | |
| SCHEMBL14728222 | 0.67 | KDM4E (0.74) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14728336 | 0.66 | MAPK1 (0.69) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14728398 | 0.66 | PDE4B (0.51) | MAPK1ALOX12HIF1AKDM4ETSHR | |
| SCHEMBL14748488 | 0.66 | MAPT (0.34) | KDM4EKMT2AMEN1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565194-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2013-03-06 | — | — | EP | disclosed |