Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.79 |
| ▸ | F3 | P13726 | 1/20 | 0.79 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.79 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.79 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.79 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.79 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.79 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.79 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL28244883 | 0.98 | F7 (0.76) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL29624874 | 0.89 | — | — | |
| Niacinamide SCHEMBL19978192 | 0.89 | — | — | |
| Niacinamide SCHEMBL2926 | 0.89 | — | — | |
| Niacinamide SCHEMBL460466 | 0.89 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL5039529 | 0.87 | SIRT2 (0.88) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL25366418 | 0.87 | — | — | |
| Niacinamide SCHEMBL11410594 | 0.87 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL6478235 | 0.87 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL1063189 | 0.87 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118922081-A | Insect, acarina and nematode pest control | 先正达农作物保护股份公司 | 2024-11-08 | — | — | CN | claimed |
| CN-104837832-B | GDF-8 inhibitors | 里格尔药品股份有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109601554-A | Including biocontrol agent and insecticide composition | 拜尔农作物科学股份公司 | 2019-04-12 | — | — | CN | claimed |
| CN-109169661-A | Composition including biocontrol agent and insecticide | 拜耳作物科学股份公司 | 2019-01-11 | — | — | CN | claimed |
| CN-109153651-A | amido-substituted cyclohexane derivatives | 拜耳制药股份公司 | 2019-01-04 | — | — | CN | claimed |
| CN-109069491-A | The positive allosteric modulators of mAChR M1 | 范德比尔特大学 | 2018-12-21 | — | — | CN | claimed |
| CN-108558867-A | Pyrrolopyridine or pyrazolo pyridine derivatives | 豪夫迈·罗氏有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-108495853-A | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS | 诺华股份有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-108358917-A | Imidazo [1,2-a] pyridine -3- amides compounds containing alkaline condensed ring segment and preparation method thereof | 北京市结核病胸部肿瘤研究所 | 2018-08-03 | — | — | CN | claimed |
| CN-103002897-B | Certain amino-pyridazines, compositions thereof, and methods of use thereof | 赛特凯恩蒂克公司 | 2017-06-09 | — | — | CN | claimed |
| CN-103384668-B | compounds and compositions for inhibition of NAMPT | 福马TM有限责任公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106588916-A | N-(phenoxyethyl) imidazo [1,2-a] pyridine-3-amide compound and preparation method thereof | 浙江司太立制药股份有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106573915-A | Compounds active against bromodomains | 纽韦卢森公司 | 2017-04-19 | — | — | CN | claimed |
| CN-105164124-B | Compounds and compositions for treating parasitic diseases | 诺华股份有限公司 | 2017-03-15 | — | — | CN | claimed |
| CN-104114553-B | Substituted pyrazolo [1,5 a] pyridine as tropomyosin receptor kinase (Trk) inhibitor | 雷迪博士实验室有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-106458996-A | Fused pyrimidines as inhibitors of the p97 complex | 克里弗生物科学公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106459070-A | Cyano containing azabenzofuran compounds for the treatment of hepatitis C | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106459048-A | Pyrazolopyridines and pyrazolopyrimidines | 辉瑞公司 | 2017-02-22 | — | — | CN | claimed |
| CN-104822680-B | Imidazopyridine | 安斯泰来制药株式会社 | 2016-10-12 | — | — | CN | claimed |