Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24553696 | 1.00 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DNFE2L2 | |
| SCHEMBL10119787 | 1.00 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DNFE2L2 | |
| SCHEMBL10110592 | 1.00 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DNFE2L2 | |
| SCHEMBL1106100 | 0.77 | — | — | |
| SCHEMBL24866883 | 0.77 | — | — | |
| SCHEMBL1106078 | 0.77 | — | — | |
| SCHEMBL10102998 | 0.74 | — | — | |
| SCHEMBL25918456 | 0.73 | — | — | |
| SCHEMBL14749986 | 0.72 | AR (0.30) | — | |
| SCHEMBL14231584 | 0.72 | AR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013031922-A1 | PYRAZOLE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 (JP) | 2013-03-07 | — | — | WO | disclosed |