Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.75 |
| ▸ | BRD4 | O60885 | 8/20 | 0.75 |
| ▸ | BRD2 | P25440 | 6/20 | 0.75 |
| ▸ | BRD3 | Q15059 | 6/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.68 |
| ▸ | CSF1R | P07333 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15985177 | 0.87 | BRD4 (0.68) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL1903177 | 0.86 | BRD4 (0.67) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL16774314 | 0.85 | BRD4 (0.58) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL18904314 | 0.85 | CYP3A4 (0.70) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL1904764 | 0.85 | BRD4 (0.68) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL13731747 | 0.84 | CYP3A4 (0.72) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL13732062 | 0.83 | BRD4 (0.69) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL1905935 | 0.83 | CYP3A4 (0.64) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL1905705 | 0.83 | BRD4 (0.63) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL2725816 | 0.83 | CYP3A4 (0.69) | CYP3A4CYP2C9BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081284-A1 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |