SCHEMBL14759099

SCHEMBL14759099

COC(=O)CNCc1cnc(Oc2ccc3c(c2)CC[C@@H](c2ccccc2)O3)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC8A1 P32418 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14759100 1.00 SLC8A1 (1.00) SLC8A1
SCHEMBL14759163 0.93 SLC8A1 (1.00) SLC8A1
SCHEMBL14759166 0.93 SLC8A1 (1.00) SLC8A1
SCHEMBL14759356 0.87 SLC8A1 (1.00) SLC8A1
SCHEMBL14759247 0.86 SLC8A1 (1.00) SLC8A1
SCHEMBL14759287 0.86 SLC8A1 (0.84) SLC8A1
SCHEMBL14759592 0.86 SLC8A1 (1.00) SLC8A1
SCHEMBL14759590 0.86 SLC8A1 (1.00) SLC8A1
SCHEMBL14759161 0.86 SLC8A1 (1.00) SLC8A1
SCHEMBL14759164 0.86 SLC8A1 (1.00) SLC8A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2755970-B1 SUBSTITUTED 2-(CHROMAN-6-YLOXY)-THIAZOLES AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2016-03-30 EP disclosed
EP-2567958-B1 Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals SANOFI SA (FR) 2014-10-29 EP disclosed
EP-2567958-A1 Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals SANOFI (FR) 2013-03-13 EP disclosed