Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14759127 | 1.00 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759369 | 0.93 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759365 | 0.93 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759702 | 0.90 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759705 | 0.90 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759548 | 0.89 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759550 | 0.89 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759285 | 0.85 | SLC8A1 (1.00) | SLC8A1 | |
| SCHEMBL14759619 | 0.84 | SLC8A1 (0.80) | SLC8A1 | |
| SCHEMBL14759250 | 0.83 | SLC8A1 (1.00) | SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755970-B1 | SUBSTITUTED 2-(CHROMAN-6-YLOXY)-THIAZOLES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2016-03-30 | — | — | EP | disclosed |
| EP-2567958-B1 | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals | SANOFI SA (FR) | 2014-10-29 | — | — | EP | disclosed |
| EP-2567958-A1 | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals | SANOFI (FR) | 2013-03-13 | — | — | EP | disclosed |