SCHEMBL14759201

SCHEMBL14759201

CN(C)C(=O)OC1CCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.44
NAAA Q02083 2/20 0.41
HTT P42858 1/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CYP2C19 P33261 1/20 0.37
BCHE P06276 2/20 0.37
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
DPP4 P27487 1/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5622283 0.98 EPHX1 (0.47) EPHX1NAAAHTTCA12CA1
SCHEMBL12292879 0.95 EPHX1 (0.39) EPHX1NAAAHTTCYP2C19BCHE
SCHEMBL25856259 0.90
SCHEMBL19312196 0.88 EPHX1 (0.41) EPHX1NAAAHTTCA12CA1
SCHEMBL2536288 0.87 BCHE (0.37) EPHX1NAAABCHECHRM4CHRM5
SCHEMBL2538352 0.87 BCHE (0.37) EPHX1NAAAHTTBCHECHRM4
SCHEMBL2531811 0.85 CHRM4 (0.37) EPHX1BCHECHRM4CHRM5CHRM1
SCHEMBL2542564 0.84 BCHE (0.35) EPHX1NAAABCHECHRM4CHRM5
SCHEMBL2541570 0.84 BCHE (0.35) EPHX1NAAABCHECHRM4CHRM5
SCHEMBL15581650 0.84 CHRM4 (0.34) EPHX1NAAABCHECHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3912974-A1 TRIAZOLE COMPOUNDS, AND PREPARATION METHOD THEREOF AND USE Wuhan LL Science And Technology Development Co., Ltd. (CN) 2021-11-24 EP disclosed
EP-3912975-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR Wuhan LL Science And Technology Development Co., Ltd. (CN) 2021-11-24 EP disclosed
WO-2020147739-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR 武汉朗来科技发展有限公司 2020-07-23 WO disclosed
WO-2020147740-A1 TRIAZOLE COMPOUNDS, AND PREPARATION METHOD THEREOF AND USE 武汉朗来科技发展有限公司 2020-07-23 WO disclosed
EP-2568019-B1 Inkjet ink JNC CORP (JP) 2015-09-02 EP disclosed
EP-2568019-A1 Inkjet ink JNC Corporation (JP) 2013-03-13 EP disclosed