SCHEMBL14759237

SCHEMBL14759237

O=C(CN1CCCC1=O)NCc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC8A1 P32418 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14759849 0.90 SLC8A1 (1.00) SLC8A1
Hydrochloric Acid SCHEMBL14759570 0.89 SLC8A1 (0.98) SLC8A1
SCHEMBL14759213 0.86 SLC8A1 (1.00) SLC8A1
SCHEMBL14759106 0.85 SLC8A1 (1.00) SLC8A1
SCHEMBL14759104 0.85 SLC8A1 (1.00) SLC8A1
SCHEMBL16192616 0.85 SLC8A1 (1.00) SLC8A1
SCHEMBL16192615 0.85 SLC8A1 (1.00) SLC8A1
SCHEMBL14759766 0.85 SLC8A1 (1.00) SLC8A1
SCHEMBL14759133 0.84 SLC8A1 (1.00) SLC8A1
SCHEMBL14759178 0.83 SLC8A1 (1.00) SLC8A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2755970-B1 SUBSTITUTED 2-(CHROMAN-6-YLOXY)-THIAZOLES AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2016-03-30 EP disclosed
EP-2567958-B1 Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals SANOFI SA (FR) 2014-10-29 EP disclosed
EP-2567958-A1 Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals SANOFI (FR) 2013-03-13 EP disclosed