Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574640 | 0.90 | KDM4E (0.78) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL18022803 | 0.84 | KDM4E (1.00) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL10483334 | 0.81 | KDM4E (0.68) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL14825491 | 0.78 | KDM4E (0.73) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL31611516 | 0.78 | KDM4E (0.72) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL12072229 | 0.78 | KDM4E (0.72) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL10061998 | 0.77 | KDM4E (0.71) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL10512800 | 0.77 | KDM4E (0.71) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL12070884 | 0.77 | KDM4E (0.70) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL14354843 | 0.77 | POLB (0.54) | MEN1KMT2APOLBTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960402-B1 | NOVEL IMIDAZOQUINAZOLINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEMICAL LTD (KR) | 2013-03-13 | — | — | EP | disclosed |