Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tosylchloramide SCHEMBL14764471 | 1.00 | GAA (0.61) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL28882248 | 1.00 | GAA (0.61) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL567565 | 1.00 | GAA (0.61) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL10526373 | 0.98 | GAA (0.59) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL696560 | 0.98 | GAA (0.59) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL6009520 | 0.98 | GAA (0.59) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL8154955 | 0.98 | GAA (0.59) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL3615720 | 0.98 | GAA (0.59) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL7225596 | 0.98 | GAA (0.59) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL10424726 | 0.98 | GAA (0.59) | GAASMN1; SMN2CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139983-A1 | [1,2,4]TRIAZOLO[4,3-A]QUINOXALINES AS DUAL PDE2/PDE10 INHIBITORS | H. LUNDBECK A/S (DK) | 2014-09-18 | — | — | WO | disclosed |
| WO-2013034755-A1 | TRIAZOLOPYRAZINE DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |