Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 4/20 | 0.43 |
| ▸ | GABRD | O14764 | 4/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.43 |
| ▸ | GABRE | P78334 | 4/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Alanine SCHEMBL43623 | 1.00 | — | — | |
| D-Alanine SCHEMBL614024 | 1.00 | SLC7A5 (0.59) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL10723495 | 1.00 | SLC7A5 (0.59) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL1332110 | 1.00 | — | — | |
| Alanine SCHEMBL31 | 1.00 | — | — | |
| Alanine SCHEMBL254290 | 1.00 | SLC7A5 (0.59) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL2784274 | 1.00 | — | — | |
| D-Alanine SCHEMBL2027760 | 1.00 | SLC7A5 (0.59) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL452350 | 1.00 | SLC7A5 (0.59) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| D-Alanine SCHEMBL31040666 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753691-B1 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INST NAT SANTE RECH MED (FR) | 2020-07-22 | — | — | EP | claimed |
| US-9249406-B2 | Mutated tissue plasminogen activators and uses thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-02-02 | — | — | US | claimed |
| US-20150050264-A2 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2015-02-19 | — | — | US | claimed |
| US-20140212406-A1 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-07-31 | — | — | US | claimed |
| WO-2013034710-A1 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2013-03-14 | — | — | WO | claimed |
| US-20230391869-A1 | INHIBITION OF PLATELET AGGREGATION USING ANTI-HUMAN GPVI ANTIBODIES | Université de Paris (FR) | 2023-12-07 | — | — | US | disclosed |
| WO-2023156683-A1 | TREATMENT OF CARDIOVASCULAR DISEASES USING ANTI-HUMAN GPVI ANTIBODIES | ACTICOR BIOTECH (FR) | 2023-08-24 | — | — | WO | disclosed |
| US-11692033-B2 | Inhibition of platelet aggregation using anti-human GPVI antibodies | ACTICOR BIOTECH (FR) | 2023-07-04 | — | — | US | disclosed |
| EP-2753691-B1 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INST NAT SANTE RECH MED (FR) | 2020-07-22 | — | — | EP | disclosed |
| US-20200138919-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE ISCHEMIC STROKE | UNIVERSITÉ PARIS CITÉ (FR) | 2020-05-07 | — | — | US | disclosed |
| WO-2018141909-A1 | INHIBITION OF PLATELET AGGREGATION USING ANTI-HUMAN GPVI ANTIBODIES | ACTICOR BIOTECH (FR) | 2018-08-09 | — | — | WO | disclosed |
| US-9732334-B2 | Mutated tissue plasminogen activators and uses thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-08-15 | — | — | US | disclosed |
| US-20160194623-A1 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-07-07 | — | — | US | disclosed |
| US-9249406-B2 | Mutated tissue plasminogen activators and uses thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-02-02 | — | — | US | disclosed |
| US-20150050264-A2 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2015-02-19 | — | — | US | disclosed |
| CN-103980348-A | Oligopeptide for diagnosing and treating hepatitis B and application of oligopeptide | CHONGQING ACADEMY SCI & TECH | 2014-08-13 | — | — | CN | disclosed |
| US-20140212406-A1 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-07-31 | — | — | US | disclosed |
| WO-2013034710-A1 | NOVEL MUTATED TISSUE PLASMINOGEN ACTIVATORS AND USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2013-03-14 | — | — | WO | disclosed |