⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764721 | 1.00 | — | — | |
| SCHEMBL27697097 | 0.76 | ELANE (0.32) | — | |
| SCHEMBL1908581 | 0.75 | NPC1 (0.35) | — | |
| SCHEMBL616550 | 0.75 | — | — | |
| SCHEMBL614538 | 0.75 | — | — | |
| SCHEMBL3835371 | 0.74 | ACACB (0.32) | — | |
| SCHEMBL13977164 | 0.74 | ACACB (0.32) | — | |
| SCHEMBL27958479 | 0.74 | PTGS1 (0.34) | — | |
| SCHEMBL616683 | 0.72 | PTGS1 (0.30) | — | |
| SCHEMBL14771565 | 0.72 | PTGS1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187942-B | Benzothiazolone compounds | 诺华股份有限公司 | 2020-06-26 | — | — | CN | disclosed |
| US-10251868-B2 | Benzothiazolone compound | NOVARTIS AG (CH) | 2019-04-09 | — | — | US | disclosed |
| US-20180140582-A1 | BENZOTHIAZOLONE COMPOUND | NOVARTIS AG (CH) | 2018-05-24 | — | — | US | disclosed |
| US-9913828-B2 | Benzothiazolone compound | NOVARTIS AG (CH) | 2018-03-13 | — | — | US | disclosed |
| EP-3243817-A1 | SALTS OF BENZOTHIAZOLONE COMPOUND AS BETA-2-ADRENOCEPTOR AGONIST | Novartis AG (CH) | 2017-11-15 | — | — | EP | disclosed |
| EP-2890687-B1 | SALTS OF BENZOTHIAZOLONE COMPOUND AS BETA-2-ADRENOCEPTOR AGONIST | NOVARTIS AG (CH) | 2017-06-28 | — | — | EP | disclosed |
| EP-2961391-B1 | FORMULATION COMPRISING BENZOTHIAZOLONE COMPOUND | NOVARTIS AG (CH) | 2017-05-17 | — | — | EP | disclosed |
| US-9623012-B2 | Formulation comprising benzothiazolone compound | NOVARTIS AG (CH) | 2017-04-18 | — | — | US | disclosed |
| CN-106187942-A | Benzothiazolone compounds | 诺华股份有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-106146428-A | Salt as the benzothiazolone compound of β 2 adrenoreceptor agonists | 诺华股份有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-103781771-B | Benzothiazolone compounds | 诺华股份有限公司 | 2016-08-24 | — | — | CN | disclosed |
| US-20160075670-A1 | BENZOTHIAZOLONE COMPOUND | NOVARTIS AG (CH) | 2016-03-17 | — | — | US | disclosed |
| US-20160000761-A1 | Formulation comprising benzothiazolone compound | NOVARTIS AG (CH) | 2016-01-07 | — | — | US | disclosed |
| US-20150336914-A1 | BENZOTHIAZOLONE COMPOUND | NOVARTIS AG (CH) | 2015-11-26 | — | — | US | disclosed |
| EP-2890687-A1 | SALTS OF BENZOTHIAZOLONE COMPOUND AS BETA-2-ADRENOCEPTOR AGONIST | Novartis AG (CH) | 2015-07-08 | — | — | EP | disclosed |
| US-20150094346-A1 | BENZOTHIAZOLONE COMPOUND | NOVARTIS AG (CH) | 2015-04-02 | — | — | US | disclosed |
| US-8933108-B2 | Benzothiazolone compound | NOVARTIS AG (CH) | 2015-01-13 | — | — | US | disclosed |
| WO-2014033654-A1 | SALTS OF BENZOTHIAZOLONE COMPOUND AS BETA-2-ADRENOCEPTOR AGONIST | NOVARTIS AG (CH) | 2014-03-06 | — | — | WO | disclosed |
| US-20130245080-A1 | BENZOTHIAZOLONE COMPOUND | NOVARTIS AG (CH) | 2013-09-19 | — | — | US | disclosed |
| WO-2013035047-A1 | BENZOTHIAZOLONE COMPOUND | NOVARTIS AG (CH) | 2013-03-14 | — | — | WO | disclosed |