Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764751 | 1.00 | PTPN1 (0.54) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL30252636 | 0.91 | PTPN1 (0.62) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL9572009 | 0.83 | PTPN1 (0.77) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL9628184 | 0.83 | PTPN1 (0.77) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL9709418 | 0.83 | PTPN1 (0.54) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL10353657 | 0.83 | PTPN1 (0.77) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL14307231 | 0.83 | PTPN1 (0.77) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL14307222 | 0.83 | PTPN1 (0.77) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL10786305 | 0.83 | PTPN1 (0.77) | PTPN1MEN1KMT2ANSD2L3MBTL1 | |
| SCHEMBL10790715 | 0.83 | PTPN1 (0.77) | PTPN1MEN1KMT2ANSD2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036766-A1 | SMALL MOLECULE NAPHTHOQUINONE- AND PHTHALIMIDE-BASED LIPOCATIONS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-03-14 | — | — | WO | disclosed |