Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acequinocyl SCHEMBL28131 | 0.87 | PTPN1 (0.48) | PTGS2PTPN1 | |
| Acequinocyl SCHEMBL4052105 | 0.87 | PTPN1 (0.48) | PTGS2PTPN1 | |
| Acequinocyl SCHEMBL29368518 | 0.87 | PTPN1 (0.48) | PTGS2PTPN1 | |
| SCHEMBL11541723 | 0.87 | PTPN1 (0.48) | PTGS2PTPN1 | |
| SCHEMBL8141388 | 0.84 | MAPT (0.37) | MAPTKDM4EMEN1KMT2APOLB | |
| Acequinocyl SCHEMBL5073435 | 0.83 | PTPN1 (0.44) | PTGS2PTPN1 | |
| SCHEMBL13991875 | 0.82 | MAPT (0.38) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL8522527 | 0.78 | MAPT (0.38) | PTGS2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14313792 | 0.77 | FGFR1 (0.50) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL8460664 | 0.77 | MAPT (0.40) | MAPTKDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036766-A1 | SMALL MOLECULE NAPHTHOQUINONE- AND PHTHALIMIDE-BASED LIPOCATIONS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-03-14 | — | — | WO | disclosed |