Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | CDC25A | P30304 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | GAPDH | P04406 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036547 | 0.98 | CDC25B (0.53) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL13611359 | 0.86 | PTPN1 (0.69) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL11247136 | 0.84 | CDC25B (0.56) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL9713908 | 0.84 | CDC25B (0.56) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL10446698 | 0.84 | PTPN1 (0.68) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL9628579 | 0.84 | CDC25B (0.56) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL9444193 | 0.83 | CDC25B (0.57) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL10446505 | 0.81 | PTPN1 (0.77) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL9628020 | 0.81 | CDC25B (0.59) | CDC25BIDO1CDC25APTPN1GAPDH | |
| SCHEMBL24597737 | 0.81 | PTPN1 (0.51) | CDC25BIDO1CDC25APTPN1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036766-A1 | SMALL MOLECULE NAPHTHOQUINONE- AND PHTHALIMIDE-BASED LIPOCATIONS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-03-14 | — | — | WO | disclosed |