Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766065 | 0.97 | KDM1A (0.36) | KDM1ASCN9APDE4APDE4BPDE4C | |
| SCHEMBL14766051 | 0.94 | KDM1A (0.40) | KDM1ASCN9APDE4APDE4BPDE4C | |
| SCHEMBL14765779 | 0.93 | KDM1A (0.40) | KDM1ASCN9APDE4APDE4BPDE4C | |
| SCHEMBL14765793 | 0.91 | KDM1A (0.32) | KDM1ASCN9APDE4APDE4BPDE4C | |
| SCHEMBL14766159 | 0.91 | ALOX5AP (0.34) | SCN9AGPR119CNR2HTR2AHTR2C | |
| SCHEMBL14766761 | 0.91 | ALOX5AP (0.34) | SCN9AGPR119CNR2HTR2AHTR2C | |
| SCHEMBL14766301 | 0.90 | SCN9A (0.33) | KDM1ASCN9AFFAR4ACACB | |
| SCHEMBL12735856 | 0.90 | SCN9A (0.40) | KDM1ASCN9APDE4APDE4BPDE4C | |
| SCHEMBL14765674 | 0.90 | KDM1A (0.41) | KDM1ASCN9APDE4APDE4BPDE4C | |
| SCHEMBL14767056 | 0.89 | FFAR1 (0.39) | SCN9AFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |