SCHEMBL14765774

SCHEMBL14765774

C=CCOc1ccc(C2CCC(CCc3ccc(C4CCC(OCC)CC4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 8/20 0.32
GPR119 Q8TDV5 2/20 0.32
MTNR1A P48039 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766966 0.95 HTR2A (0.33) MTNR1A
SCHEMBL14765894 0.91 OPRL1 (0.31) OPRL1GPR119
SCHEMBL14766328 0.90 OPRL1 (0.35) OPRL1GPR119
SCHEMBL12735048 0.90 OPRL1 (0.33) OPRL1MTNR1A
SCHEMBL14766085 0.89 HTR2A (0.33) GPR119MTNR1A
SCHEMBL14766805 0.88 HTR2C (0.35)
SCHEMBL14765760 0.88 HTR2C (0.35)
SCHEMBL10302120 0.87 OPRL1 (0.34) OPRL1MTNR1A
SCHEMBL14766412 0.86
SCHEMBL14766448 0.86 FFAR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed