SCHEMBL14765879

SCHEMBL14765879

C=CCCOc1ccc(-c2ccc(COc3ccc(-c4ccc(OCC)cc4)c(F)c3F)cc2)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.37
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HTR1A P08908 1/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
FFAR1 O14842 4/20 0.34
FFAR4 Q5NUL3 2/20 0.34
CNR1 P21554 1/20 0.34
PPARD Q03181 2/20 0.34
GABRA1 P14867 4/20 0.34
GABRB2 P47870 4/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
MAPT P10636 3/20 0.33
NPC1 O15118 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767195 1.00 CNR2 (0.37) CNR2CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL14765970 0.93 CNR2 (0.42) CNR2CYP1A2CYP2D6CYP2C19L3MBTL1
SCHEMBL14767181 0.93 CNR2 (0.42) CNR2CYP1A2CYP2D6CYP2C19L3MBTL1
SCHEMBL14766499 0.93 FFAR1 (0.43) CNR2FFAR1FFAR4CNR1PPARD
SCHEMBL14766182 0.92 FFAR1 (0.40) CNR2FFAR1FFAR4PPARDGABRA1
SCHEMBL14767238 0.90 FFAR1 (0.44) CNR2FFAR1FFAR4PPARDPPARG
SCHEMBL14767082 0.90 FFAR1 (0.46) CNR2FFAR1FFAR4PPARDPPARG
SCHEMBL14767297 0.90 CNR2 (0.43) CNR2CYP1A2CYP2D6CYP2C19L3MBTL1
SCHEMBL14766373 0.90 CNR2 (0.43) CNR2CYP1A2CYP2D6CYP2C19L3MBTL1
SCHEMBL14766800 0.89 FFAR1 (0.46) CNR2FFAR1FFAR4CNR1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed