Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766032 | 0.98 | RARB (0.46) | RARBRARAS1PR1FAAHMAPT | |
| SCHEMBL14766300 | 0.97 | RARB (0.47) | RARBRARAS1PR1FAAHMAPT | |
| SCHEMBL14766452 | 0.93 | RARB (0.42) | RARBRARAS1PR1FAAHMAPT | |
| SCHEMBL12737526 | 0.93 | S1PR1 (0.46) | RARBRARAS1PR1MAPTKMT2A | |
| SCHEMBL14766408 | 0.93 | RARB (0.42) | RARBRARAS1PR1FAAHMAPT | |
| SCHEMBL14766045 | 0.91 | MAPT (0.48) | RARBMAPTKMT2APTPN11FFAR1 | |
| SCHEMBL14767282 | 0.91 | MAPT (0.48) | RARBMAPTKMT2APTPN11FFAR1 | |
| SCHEMBL14766610 | 0.90 | MAPT (0.48) | MAPTKMT2AFFAR1FFAR4THRB | |
| SCHEMBL14766984 | 0.90 | KMT2A (0.48) | RARBRARAFAAHMAPTKMT2A | |
| SCHEMBL12737527 | 0.90 | PTPN11 (0.45) | RARBS1PR1PTPN11THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |