SCHEMBL14766145

SCHEMBL14766145

CCCCOc1ccc(-c2ccc(COc3ccc(C4CCC(OCCCC)CC4)c(F)c3F)cc2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 3/20 0.39
S1PR3 Q99500 2/20 0.39
F10 P00742 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
HTR1A P08908 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
CRHBP P24387 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
CRHR2 Q13324 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FFAR4 Q5NUL3 3/20 0.34
FFAR1 O14842 4/20 0.34
PPARD Q03181 2/20 0.34
ALOX5 P09917 1/20 0.33
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765913 0.97 S1PR1 (0.39) S1PR1S1PR3F10NR1H4HTR1A
SCHEMBL14766091 0.97 S1PR1 (0.37) S1PR1S1PR3F10NR1H4HTR1A
SCHEMBL14766234 0.94 S1PR1 (0.36) S1PR1S1PR3F10NR1H4HTR1A
SCHEMBL14766617 0.94 FFAR1 (0.37) S1PR1S1PR3F10HTR1ASLC6A2
SCHEMBL14766042 0.93 S1PR1 (0.35) S1PR1S1PR3F10NR1H4HTR1A
SCHEMBL12736426 0.92 S1PR1 (0.40) S1PR1S1PR3F10NR1H4HTR1A
SCHEMBL14766959 0.91 FFAR1 (0.38) S1PR1S1PR3F10HTR1ASLC6A2
SCHEMBL14766765 0.91 FFAR1 (0.39) S1PR1S1PR3F10HTR1ASLC6A2
SCHEMBL12736433 0.90 S1PR1 (0.39) S1PR1S1PR3F10NR1H4HTR1A
SCHEMBL14767111 0.90 FFAR1 (0.38) F10FFAR4FFAR1PPARDNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed