Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | TSPO | P30536 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12822542 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL14922550 | 0.95 | MAPT (0.40) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL15381720 | 0.91 | MAPT (0.37) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL14767243 | 0.91 | MAPT (0.37) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL15381579 | 0.91 | MAPT (0.37) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12737601 | 0.91 | MAPT (0.37) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12741064 | 0.91 | MAPT (0.37) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL14766350 | 0.91 | MAPT (0.37) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 | |
| SCHEMBL12823119 | 0.90 | KDM1A (0.40) | SMN1; SMN2MAPTCAMKK1CAMKK2NAAA | |
| SCHEMBL12741055 | 0.90 | CYP19A1 (0.38) | SMN1; SMN2MAPTCAMKK1CAMKK2MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |