Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766974 | 0.97 | GLA (0.36) | GLASMN1; SMN2SCN9APPARGS1PR1 | |
| SCHEMBL14766674 | 0.94 | GLA (0.35) | GLASMN1; SMN2SCN9APPARGS1PR1 | |
| SCHEMBL14766624 | 0.91 | GLA (0.32) | GLASMN1; SMN2SCN9APPARGS1PR1 | |
| SCHEMBL14766317 | 0.91 | KDM1A (0.37) | KDM1ASMN1; SMN2HCRTR1HCRTR2CALM1 | |
| SCHEMBL14766891 | 0.90 | SCN9A (0.33) | GLASMN1; SMN2SCN9APPARGS1PR1 | |
| SCHEMBL12739714 | 0.90 | KDM1A (0.36) | KDM1AS1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL12739711 | 0.89 | KDM1A (0.38) | KDM1ASMN1; SMN2HCRTR1HCRTR2CALM1 | |
| SCHEMBL14766400 | 0.88 | DRD4 (0.37) | KDM1ASCN9APPARGS1PR1S1PR2 | |
| SCHEMBL12739724 | 0.87 | GLA (0.37) | GLASMN1; SMN2SCN9APPARGS1PR1 | |
| SCHEMBL14766737 | 0.87 | BACE1 (0.39) | KDM1AHCRTR1HCRTR2CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |