Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767024 | 0.96 | CNR2 (0.43) | CNR2S1PR1CNR1S1PR3FAAH | |
| SCHEMBL14767000 | 0.92 | CNR2 (0.43) | CNR2S1PR1CNR1FAAHRARB | |
| SCHEMBL14766902 | 0.91 | S1PR1 (0.45) | CNR2S1PR1S1PR3FAAHSMN1; SMN2 | |
| SCHEMBL14766604 | 0.91 | FFAR1 (0.38) | CNR2S1PR1CNR1FFAR1FFAR4 | |
| SCHEMBL14766003 | 0.90 | S1PR1 (0.43) | CNR2S1PR1CNR1S1PR3FAAH | |
| SCHEMBL14766756 | 0.89 | FFAR4 (0.42) | S1PR1S1PR3FAAHSMN1; SMN2GLA | |
| SCHEMBL14766695 | 0.89 | S1PR1 (0.44) | CNR2S1PR1S1PR3FAAHSMN1; SMN2 | |
| SCHEMBL14767298 | 0.89 | CNR2 (0.42) | CNR2S1PR1CNR1S1PR3FAAH | |
| SCHEMBL12740155 | 0.88 | FFAR4 (0.38) | CNR2S1PR1CNR1S1PR3FFAR1 | |
| SCHEMBL14766295 | 0.88 | CNR2 (0.43) | CNR2S1PR1CNR1S1PR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |