Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766057 | 0.97 | S1PR1 (0.42) | S1PR1S1PR3FFAR1FFAR4MCL1 | |
| SCHEMBL14765915 | 0.96 | FFAR1 (0.47) | S1PR1S1PR3FFAR1FFAR4MCL1 | |
| SCHEMBL12737133 | 0.95 | FFAR1 (0.42) | S1PR1S1PR3FFAR1FFAR4MCL1 | |
| SCHEMBL14766745 | 0.95 | FFAR1 (0.43) | S1PR1S1PR3FFAR1FFAR4MCL1 | |
| SCHEMBL12737134 | 0.93 | FFAR1 (0.41) | S1PR1S1PR3FFAR1FFAR4MCL1 | |
| SCHEMBL14766810 | 0.92 | FFAR1 (0.42) | S1PR1S1PR3FFAR1FFAR4MCL1 | |
| SCHEMBL12737136 | 0.92 | PTPN11 (0.42) | S1PR1S1PR3FFAR1FFAR4PTPN11 | |
| SCHEMBL12737135 | 0.92 | PTPN11 (0.42) | S1PR1S1PR3FFAR1FFAR4PTPN11 | |
| SCHEMBL12737137 | 0.92 | PTPN11 (0.42) | S1PR1S1PR3FFAR1FFAR4PTPN11 | |
| SCHEMBL10302503 | 0.91 | S1PR1 (0.42) | S1PR1S1PR3FFAR1FFAR4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |