SCHEMBL14766780

SCHEMBL14766780

CCCCOc1ccc(-c2ccc(C3CCC(CCc4ccc(OCC)cc4F)CC3)c(F)c2F)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.39
FFAR1 O14842 3/20 0.39
S1PR1 P21453 2/20 0.36
S1PR3 Q99500 2/20 0.36
CNR2 P34972 2/20 0.34
PPARD Q03181 1/20 0.34
HTR2A P28223 1/20 0.33
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
CRBN Q96SW2 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
MCL1 Q07820 1/20 0.32
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766818 0.97 FFAR4 (0.38) FFAR4FFAR1S1PR1S1PR3CNR2
SCHEMBL14766384 0.95 FFAR4 (0.37) FFAR4FFAR1S1PR1S1PR3CNR2
SCHEMBL14766640 0.95 FFAR4 (0.37) FFAR4FFAR1PPARDHTR2A
SCHEMBL14765997 0.94 FFAR4 (0.41) FFAR4FFAR1S1PR1S1PR3CNR2
SCHEMBL12739915 0.93 CYP2C9 (0.37) FFAR4FFAR1S1PR1S1PR3CNR2
SCHEMBL14766397 0.92 FFAR4 (0.34) FFAR4FFAR1S1PR1S1PR3CNR2
SCHEMBL12739904 0.92 FFAR4 (0.40) FFAR4FFAR1S1PR1S1PR3CNR2
SCHEMBL12739917 0.91 CNR2 (0.37) FFAR4FFAR1S1PR1S1PR3CNR2
SCHEMBL12739902 0.91 FFAR4 (0.38) FFAR4FFAR1S1PR1S1PR3HTR2A
SCHEMBL14765962 0.90 FFAR4 (0.37) FFAR4FFAR1S1PR1S1PR3CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed