SCHEMBL14766801 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	FFAR4	Q5NUL3	8/20	0.39

▸	S1PR1	P21453	2/20	0.39

▸	S1PR3	Q99500	2/20	0.39

▸	HTR2A	P28223	2/20	0.35

▸	FFAR1	O14842	2/20	0.33

▸	PTPN11	Q06124	1/20	0.33

▸	RARB	P10826	2/20	0.33

▸	RARA	P10276	1/20	0.33

▸	CRBN	Q96SW2	1/20	0.33

▸	MCL1	Q07820	1/20	0.32

▸	C3AR1	Q16581	1/20	0.32

▸	CNR2	P34972	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14766961	0.97	FFAR4 (0.39)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14766590	0.97	FFAR4 (0.39)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14766875	0.94	FFAR4 (0.36)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14765993	0.94	S1PR1 (0.42)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14766879	0.93	FFAR4 (0.36)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14765828	0.91	S1PR1 (0.42)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14766265	0.91	S1PR1 (0.40)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL12740057	0.91	FFAR4 (0.40)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14766856	0.90	FFAR4 (0.40)	FFAR4S1PR1S1PR3HTR2AFFAR1
SCHEMBL14766903	0.90	FFAR4 (0.39)	FFAR4S1PR1S1PR3HTR2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8394294-B2	Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device	JNC CORPORATION (JP)	2013-03-12	—	—	US	disclosed