SCHEMBL14766804

SCHEMBL14766804

CCCCOc1ccc(-c2ccc(CCc3ccc(C4=CCC(OCCC)CC4)c(F)c3F)cc2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 3/20 0.40
S1PR3 Q99500 2/20 0.40
RARB P10826 2/20 0.33
C3AR1 Q16581 1/20 0.31
PTPN11 Q06124 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
CCNT1 O60563 1/20 0.31
CDK9 P50750 1/20 0.31
RARA P10276 1/20 0.31
CRBN Q96SW2 1/20 0.30
FFAR1 O14842 2/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766634 0.97 S1PR1 (0.41) S1PR1S1PR3RARBPTPN11FFAR4
SCHEMBL14766340 0.94 S1PR1 (0.38) S1PR1S1PR3RARBFFAR4CCNT1
SCHEMBL14766990 0.91 S1PR1 (0.37) S1PR1S1PR3RARB
SCHEMBL14767040 0.91 S1PR1 (0.37) S1PR1S1PR3RARB
SCHEMBL14766662 0.89 S1PR1 (0.33) S1PR1S1PR3FFAR4FFAR1
SCHEMBL12738766 0.89 S1PR1 (0.42) S1PR1S1PR3RARBC3AR1PTPN11
SCHEMBL14766981 0.88 CCNT1 (0.33) CCNT1CDK9
SCHEMBL14766933 0.87 S1PR1 (0.38) S1PR1RARBCCNT1CDK9RARA
SCHEMBL12738769 0.87 S1PR1 (0.41) S1PR1S1PR3RARBPTPN11FFAR4
SCHEMBL12738777 0.86 S1PR1 (0.40) S1PR1S1PR3RARBPTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed