SCHEMBL14766865

SCHEMBL14766865

CCOc1ccc(-c2ccc(-c3ccc(COc4ccc(OCC)cc4F)cc3)c(F)c2F)cc1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 16/20 0.52
PPARD Q03181 8/20 0.52
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
FFAR4 Q5NUL3 2/20 0.43
GSTP1 P09211 1/20 0.39
CACNA1C Q13936 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767069 0.96 FFAR1 (0.54) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL12741006 0.95 FFAR1 (0.47) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL14766857 0.94 FFAR1 (0.47) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL12741014 0.94 FFAR1 (0.49) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL12741015 0.94 FFAR1 (0.47) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL12823868 0.94 FFAR1 (0.47) FFAR1PPARDPPARA
SCHEMBL14765896 0.94 FFAR1 (0.46) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL12741007 0.93 FFAR1 (0.46) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL14766172 0.91 FFAR1 (0.49) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL14767096 0.91 FFAR1 (0.45) FFAR1PPARDPPARGPPARAFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed