Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766688 | 0.98 | FFAR4 (0.34) | HDAC8FFAR4RARARARBFFAR1 | |
| SCHEMBL14766746 | 0.95 | FFAR4 (0.38) | HDAC8FFAR4RARARARBFFAR1 | |
| SCHEMBL12739301 | 0.94 | CYP2C9 (0.33) | HDAC8FFAR4RARARARBFFAR1 | |
| SCHEMBL14766101 | 0.93 | FFAR4 (0.35) | HDAC8FFAR4RARARARBFFAR1 | |
| SCHEMBL14766364 | 0.92 | HDAC8 (0.33) | HDAC8FFAR4RARARARBFFAR1 | |
| SCHEMBL14766952 | 0.92 | HDAC8 (0.31) | HDAC8FFAR4RARARARBFFAR1 | |
| SCHEMBL12739304 | 0.92 | HDAC8 (0.34) | HDAC8CRBNS1PR1S1PR3MCL1 | |
| SCHEMBL12739307 | 0.91 | PTPN11 (0.35) | HDAC8CRBNPTPN11 | |
| SCHEMBL12739312 | 0.91 | PTPN11 (0.35) | HDAC8CRBNPTPN11 | |
| SCHEMBL12739308 | 0.91 | PTPN11 (0.35) | HDAC8CRBNPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |