SCHEMBL14767290

SCHEMBL14767290

C=CCCOc1ccc(OCC2CCC(c3ccc(-c4ccc(OCC)cc4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 13/20 0.38
PPARD Q03181 12/20 0.38
FFAR4 Q5NUL3 5/20 0.35
PPARA Q07869 1/20 0.33
PDE4D Q08499 1/20 0.32
SSTR5 P35346 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766681 0.97 FFAR1 (0.40) FFAR1PPARDFFAR4PPARASSTR5
SCHEMBL14767103 0.95 FFAR1 (0.38) FFAR1PPARDFFAR4PPARA
SCHEMBL14765816 0.94 FFAR1 (0.37) FFAR1PPARDFFAR4PDE4DSSTR5
SCHEMBL14767125 0.93 FFAR1 (0.38) FFAR1PPARDFFAR4PPARA
SCHEMBL14766774 0.92 FFAR1 (0.39) FFAR1PPARDFFAR4PPARA
SCHEMBL12740800 0.92 PPARD (0.38) FFAR1PPARDFFAR4PPARA
SCHEMBL14766699 0.92 ALOX5AP (0.33) FFAR1PPARDFFAR4PDE4DSSTR5
SCHEMBL14765781 0.92 ALOX5AP (0.33) FFAR1PPARDFFAR4PDE4DSSTR5
SCHEMBL14767107 0.91 PPARD (0.39) FFAR1PPARDFFAR4PPARAPDE4D
SCHEMBL14766561 0.91 FFAR1 (0.43) FFAR1PPARDFFAR4PPARAPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed