Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.56 |
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.36 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.36 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.36 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.36 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.36 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767620 | 1.00 | PTPN2 (0.56) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL14767666 | 0.92 | PTPN1 (0.61) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL14767672 | 0.89 | PTPN2 (0.59) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL13015023 | 0.89 | PTPN1 (0.59) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL14767629 | 0.89 | PTPN2 (0.59) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL14767652 | 0.85 | HIF1A (0.59) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL31508572 | 0.85 | HIF1A (0.59) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL11886113 | 0.85 | HIF1A (0.59) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL17849951 | 0.84 | HIF1A (0.58) | PTPN2PTPN1DUSP3PTPRCHIF1A | |
| SCHEMBL14767592 | 0.84 | HIF1A (0.58) | PTPN2PTPN1DUSP3PTPRCHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371301-B2 | Prenylarene compound and use thereof | OSAKA UNIVERSITY (JP) | 2016-06-21 | — | — | US | disclosed |
| US-9371301-B2 | Prenylarene compound and use thereof | OSAKA UNIVERSITY (JP) | 2016-06-21 | — | — | US | disclosed |
| US-20130065937-A1 | NOVEL PRENYLARENE COMPOUND AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130065937-A1 | NOVEL PRENYLARENE COMPOUND AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2013-03-14 | — | — | US | disclosed |
| EP-2567956-A1 | NOVEL PRENYLARENE COMPOUND AND USE THEREOF | Osaka University (JP) | 2013-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065937-A1 | NOVEL PRENYLARENE COMPOUND AND USE THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NR1H3, HIF1AN | PTPN2 4565/4885PTPN1 4526/4885DUSP3 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.