⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631996 | 0.73 | GBA1 (0.47) | — | |
| SCHEMBL14596390 | 0.70 | GANAB (0.43) | — | |
| SCHEMBL24547699 | 0.65 | GAA (0.56) | — | |
| SCHEMBL20404217 | 0.65 | — | — | |
| SCHEMBL25841196 | 0.65 | — | — | |
| SCHEMBL4378244 | 0.65 | — | — | |
| SCHEMBL10077217 | 0.64 | — | — | |
| SCHEMBL14296371 | 0.64 | — | — | |
| SCHEMBL25668904 | 0.64 | — | — | |
| SCHEMBL25597480 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013037390-A1 | 6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | SANOFI (FR) | 2013-03-21 | — | — | WO | disclosed |
| EP-2567959-A1 | 6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2013-03-13 | — | — | EP | disclosed |